The Chen Lab

Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions

A non-canonical Notch complex regulates adherens junctions and vascular barrier function

Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell–endothelial cell-regulated barrier...

3D-printed vascular networks direct therapeutic angiogenesis in ischaemia. PDF

Mechanosensing in fibrillar microenvironments PDF

Check out John and Anant's Science article: Titin Mutations in iPS cells Define Sarcomere Insufficiency as a Cause of Dilated Cardiomyopathy

Check out Brandon and Britta's paper at Nature Methods, A DNA-based molecular probe for optically reporting cellular traction forces.

Pete's paper, Fluid shear stress threshold regulates angiogenic sprouting, is out on PNAS.

Jan, Ritu, and Kelly have a paper PNAS: Geometric control of vascular networks to enhance engineered tissue integration and function

Check out Duc and Sarah's paper on PNAS: Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro

Check out Wendy's new E-cadherin paper in Journal of Cell Biology, E-cadherin engagement stimulates proliferation via Rac1